|
|
|
What is glycogen storage disease? Glycogen storage diseases (GSDs) are a bunch of rare circumstances in which your body can’t use or store glycogen properly. They’re varieties of inherited (handed from guardian to child) metabolic disorders. Advertising on our site helps assist our mission. We don't endorse non-Cleveland Clinic products or services. Glycogen is the stored type of glucose (sugar). Glucose is your body’s primary source of power. It comes from carbohydrates (a macronutrient) in sure foods and fluids you consume. When your body doesn’t instantly want glucose for power, it stores glucose primarily in your skeletal muscles and liver as glycogen for later use. Your body creates glycogen from glucose through a course of known as glycogenesis. When your physique needs further gas, it breaks down glycogen for use via a process known as glycogenolysis. Several enzymes are responsible for these two processes. Glycogen storage diseases occur if you don’t have a number of of those enzymes. Your body can’t use stored glycogen for energy or maintain regular blood glucose levels. This can cause a number of points, together with frequent symptomatic low Healthy Flow Blood sugar (hypoglycemia), liver damage and muscle weakness. Researchers know more about some varieties than others. GSD principally impacts your liver or muscles. Some varieties trigger problems in other areas of your physique, as well. For each sort of GSD, there’s an absence (deficiency) of a sure enzyme involved in glycogen storage or breakdown. Healthcare suppliers could refer to each type based on the particular enzyme that’s lacking or the scientist who found that kind of GSD. Glycogen storage disease is rare. GSD sort I (von Gierke illness), the commonest kind, happens in approximately 1 in 100,000 births. |
|
發表於